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KMID : 0363219950330061129
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Korean Journal of Dermatology
1995 Volume.33 No. 6 p.1129 ~ p.1133
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A Case of Wegener's Granulomaosis
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김수정
박상훈/이광훈/방동식/이수곤
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Abstract
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Wegener's granulomatosis is a systemic necrotizing vasculitis of unknown cause. The disease is characterized by the involvement of the upper airway, the lung. and the kidney. Skin lesions are frequent and the most common lesion is purpura
dlstributed on
the limbs and trunk.
A 34-year-old female showed recurrent purpuric macules on the both lower extremities and buttocks. The patient showed nasal septal perforation with saddle nose deformity and C-ANCA positivity Histopathologic findings of purpuric lesion revealed
the
features of necrotizing vasculitis. The histologic specimen from the nasal cavity showed chronic inflammation with granuloma formation and kidney showed focal necrotizing glomerulonephritis. Therefore, we treated the patient with prednisolone and
cyclophosphamide having diagnosed Wegener's granulomatosis.
(Kor J Dermatol 1995;33(6) : 1129~1133)
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KEYWORD
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